Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816335 | 0.79 | POLB (0.53) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL3759447 | 0.78 | POLB (0.55) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL3759450 | 0.78 | POLB (0.55) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL17237808 | 0.77 | TSHR (0.37) | POLBALDH1A1 | |
| SCHEMBL17237810 | 0.77 | TSHR (0.37) | POLBALDH1A1 | |
| SCHEMBL32688847 | 0.76 | POLB (0.55) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL21896029 | 0.76 | POLB (0.50) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL32689185 | 0.76 | POLB (0.55) | POLBHSD11B1HPGDL3MBTL1EPHX2 | |
| SCHEMBL11601506 | 0.76 | NPC1 (0.50) | POLBHSD11B1HPGDL3MBTL1NPC1 | |
| SCHEMBL21896031 | 0.75 | POLB (0.57) | POLBHSD11B1HPGDL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |