Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819322 | 1.00 | CCKBR (0.72) | CCKBR | |
| SCHEMBL9372867 | 0.91 | CCKBR (0.81) | CCKBR | |
| SCHEMBL8881976 | 0.90 | CCKBR (0.66) | CCKBR | |
| SCHEMBL9279156 | 0.90 | CCKBR (0.66) | CCKBR | |
| SCHEMBL7808664 | 0.90 | CCKBR (0.84) | CCKBR | |
| SCHEMBL7816148 | 0.90 | CCKBR (0.84) | CCKBR | |
| SCHEMBL9369628 | 0.84 | CCKBR (0.88) | CCKBR | |
| SCHEMBL7816049 | 0.84 | CCKBR (0.79) | CCKBR | |
| SCHEMBL9125008 | 0.84 | CCKBR (0.87) | CCKBR | |
| SCHEMBL9368456 | 0.84 | CCKBR (1.00) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652871-B1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-10-17 | — | — | EP | claimed |
| EP-0652871-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1995-05-17 | — | — | EP | claimed |
| WO-1994003437-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| EP-0652871-B1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-5618812-A | GASTRIN ANTAGONISTS; GASTROINTESTINAL DISORDERS | MERCK SHARP & DOHME, LTD. (GB) | 1997-04-08 | — | — | US | disclosed |
| WO-1994003437-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |