Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978150 | 0.79 | HDAC1 (0.41) | HDAC1HDAC6 | |
| SCHEMBL15158946 | 0.77 | POLB (0.38) | ACHEPOLBTOP2A | |
| SCHEMBL2265282 | 0.76 | — | — | |
| SCHEMBL29300304 | 0.75 | ACHE (0.34) | ACHEPOLBTOP2A | |
| SCHEMBL11859724 | 0.75 | ACHE (0.38) | ACHEPOLBTOP2A | |
| SCHEMBL12763757 | 0.75 | MEN1 (0.35) | ACHEPOLBADORA2AADORA2BADORA3 | |
| SCHEMBL7603719 | 0.75 | ACHE (0.34) | ACHEPOLBTOP2A | |
| SCHEMBL15423507 | 0.73 | ACHE (0.33) | ACHEPOLB | |
| SCHEMBL19447778 | 0.73 | ACHE (0.33) | ACHEPOLB | |
| SCHEMBL2265756 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1791655-A | Organic phosphorescent material and organic optoelectronic device | ISIS INNOVATION (GB) | 2006-06-21 | — | — | CN | disclosed |
| EP-0500864-B1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| US-5292749-A | Quinuclidine derivatives; bronchodilator agents, treatment of respiratory system disorders | PFIZER INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0500864-A1 | ANTIMUSCARINIC BRONCHODILATORS | Pfizer Limited (GB) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004346-A1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |