Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544912 | 0.80 | CYP4F2 (0.71) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL129800 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL23635693 | 0.79 | CYP4F2 (0.64) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL27980684 | 0.79 | CYP4F2 (0.64) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL129801 | 0.78 | CYP4F2 (0.71) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL4508966 | 0.77 | CYP4F2 (0.66) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL27925942 | 0.77 | CYP4F2 (0.58) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL28245975 | 0.76 | CYP4F2 (0.57) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL128387 | 0.75 | CYP4F2 (0.72) | CYP4F2CYP4A11RAB9AMAPTNPC1 | |
| SCHEMBL2089661 | 0.75 | CYP4F2 (0.68) | CYP4F2CYP4A11RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |