Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282592 | 1.00 | TDP1 (0.32) | TDP1 | |
| SCHEMBL19412828 | 0.78 | — | — | |
| SCHEMBL11038350 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL13534568 | 0.71 | — | — | |
| SCHEMBL13702975 | 0.71 | — | — | |
| SCHEMBL13702976 | 0.71 | — | — | |
| SCHEMBL13534564 | 0.71 | — | — | |
| SCHEMBL7247882 | 0.71 | TDP1 (0.35) | TDP1 | |
| SCHEMBL441317 | 0.70 | — | — | |
| SCHEMBL19491569 | 0.70 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112268-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015633-A1 | CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-23 | — | — | WO | disclosed |
| EP-0228061-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-07-08 | — | — | EP | disclosed |
| US-4639436-A | Antidiabetic 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0193770-A2 | 3,4,5-Trihydroxypiperidine, process for their preparation and their use | BAYER AG (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0000947-B2 | 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM | BAYER AG (DE) | 1984-10-10 | — | — | EP | disclosed |
| EP-0008058-B1 | N-AMINO-3,4,5-TRIHYDROXYPIPERIDINES, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, METHOD FOR THE PRODUCTION OF THE MEDICAMENTS AND ANIMAL FEEDSTUFF CONTAINING SAID COMPOUNDS | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4293551-A | N-Amino-3,4,5-trihydroxypiperidines, their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4260622-A | Animal feedstuffs employing 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0000947-B1 | 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM | BAYER AG (DE) | 1981-01-14 | — | — | EP | disclosed |
| US-4199572-A | DERIVATIVES OF SISOMICINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-22 | — | — | US | disclosed |
| EP-0008058-A1 | N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |