SCHEMBL7817581

SCHEMBL7817581

C#CCC(CC(=O)O)OC=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
GABRR1 P24046 2/20 0.30
LMNA P02545 2/20 0.30
SLC22A6 Q4U2R8 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15480932 0.76 GRIK1 (0.33) GRIK1GRIK2LMNASLC22A6SMN1; SMN2
SCHEMBL14446798 0.74 LMNA (0.36) GABRR1LMNASLC22A6SMN1; SMN2
SCHEMBL7255396 0.74
SCHEMBL27952271 0.69 LMNA (0.58) LMNASMN1; SMN2
SCHEMBL18541180 0.68 GRIK1 (0.34) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL28006914 0.68 SLC22A6 (0.39) GRIK1GRIK2GABRR1LMNASLC22A6
SCHEMBL4747485 0.66
SCHEMBL4747479 0.66
SCHEMBL15031954 0.66
SCHEMBL762292 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112268-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-07-04 EP disclosed
WO-2000015633-A1 CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-23 WO disclosed