Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300796 | 0.95 | TACR1 (0.59) | TACR1 | |
| SCHEMBL7846541 | 0.90 | TACR1 (0.60) | TACR1 | |
| SCHEMBL7956549 | 0.87 | TACR1 (0.49) | TACR1 | |
| SCHEMBL8484370 | 0.83 | TACR1 (0.50) | TACR1 | |
| SCHEMBL4630790 | 0.82 | TACR1 (0.44) | TACR1 | |
| SCHEMBL8589071 | 0.82 | TACR1 (0.52) | TACR1 | |
| SCHEMBL7811978 | 0.82 | TACR2 (0.62) | TACR1 | |
| SCHEMBL8970672 | 0.81 | TACR1 (0.47) | TACR1 | |
| SCHEMBL7765734 | 0.79 | TACR1 (0.40) | TACR1 | |
| SCHEMBL8567221 | 0.79 | TACR1 (0.51) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775132-B1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | PFIZER LTD (GB) | 2001-03-28 | — | — | EP | disclosed |
| US-5968923-A | ANTIINFLAMMATORY AGENTS, TREATMENT OF NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS | PFIZER INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1996005193-A1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |