Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.38 |
| ▸ | TUBB | P07437 | 5/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817877 | 1.00 | PTAFR (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7817886 | 1.00 | PTAFR (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7818022 | 0.93 | PTPN1 (0.40) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7818014 | 0.93 | PTPN1 (0.40) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7807600 | 0.91 | TUBB4A (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL8887187 | 0.91 | TUBB4A (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7821438 | 0.91 | TUBB1 (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7807588 | 0.91 | TUBB4A (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL8887199 | 0.91 | TUBB4A (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7807592 | 0.91 | TUBB4A (0.45) | PTAFRACHEPTPN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574510-B1 | 2,4-DIARYL-1,3-DITHIOLANES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CT FOR INNOVATIVE TECHNOLOGY (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5639782-A | ANTIINFLAMMATORY AGENT; ANTIALLERGENS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015294-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1992-09-17 | — | — | WO | disclosed |