Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581306 | 0.83 | KDM4E (0.35) | KDM4EAKR1B1POLBAPEX1RECQL | |
| SCHEMBL9838859 | 0.71 | KDM4E (0.42) | KDM4EAKR1B1POLBAPEX1RECQL | |
| SCHEMBL7153475 | 0.70 | KDM4E (0.50) | KDM4ECTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL7171872 | 0.70 | KDM4E (0.50) | KDM4EAKR1B1POLBAPEX1RECQL | |
| SCHEMBL17567325 | 0.70 | KDM4E (0.50) | KDM4EAKR1B1CTNNB1WNT3ANPC1 | |
| SCHEMBL1347343 | 0.68 | CTNNB1 (0.58) | KDM4ERECQLCTNNB1WNT3ANPC1 | |
| SCHEMBL25745514 | 0.68 | KDM4E (0.49) | KDM4EAKR1B1POLBAPEX1RECQL | |
| SCHEMBL31085181 | 0.68 | KDM4E (0.49) | KDM4EAKR1B1CTNNB1WNT3ANPC1 | |
| SCHEMBL1907961 | 0.68 | KDM4E (0.49) | KDM4EAKR1B1CTNNB1WNT3ANPC1 | |
| SCHEMBL6802218 | 0.67 | KDM4E (0.38) | KDM4EAKR1B1POLBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841337-B1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| EP-0841337-A1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |