Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577663 | 0.85 | LMNA (0.37) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL7818102 | 0.83 | KDM4E (0.40) | KDM4EAKR1B1ALDH1A1POLBRECQL | |
| SCHEMBL7202177 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL9259019 | 0.80 | LMNA (0.37) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL6040443 | 0.77 | ALPG (0.42) | KDM4EAKR1B1CREBBPALDH1A1POLB | |
| SCHEMBL7203233 | 0.68 | CYP4F2 (0.47) | KDM4EALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL7153475 | 0.67 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL703438 | 0.66 | CA12 (0.53) | KDM4EALDH1A1RECQLSMN1; SMN2MAPT | |
| SCHEMBL9255523 | 0.65 | CYP4F2 (0.47) | KDM4EALDH1A1POLBRECQLSMN1; SMN2 | |
| SCHEMBL31085256 | 0.65 | KDM4E (0.45) | KDM4EAKR1B1CREBBPALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |