SCHEMBL7818282

SCHEMBL7818282

CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=NO)C3)c(F)c2)C(=O)O1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.71
MAOB P27338 6/20 0.71
PTGS1 P23219 2/20 0.71
SDHA P31040 2/20 0.71
LMNA P02545 1/20 0.71
CALML3 P27482 1/20 0.71
F10 P00742 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27361465 1.00 MAOA (0.71) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7818278 1.00 MAOA (0.71) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6188752 0.95 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6188758 0.95 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7812561 0.93 MAOA (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7812564 0.93 MAOA (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7814931 0.91 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL27387037 0.91 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6988646 0.89 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6988639 0.89 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788498-B1 PHENYLOXAZOLIDINONE ANTIMICROBIALS UPJOHN CO (US) 2001-08-16 EP disclosed
CN-1162312-A Phenyloxazolidinone antimicrobials PHARMACIA & UPJOHN CO LLC (US) 1997-10-15 CN disclosed
EP-0788498-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1997-08-13 EP disclosed
WO-1996013502-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1996-05-09 WO disclosed