Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9926022 | 0.67 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL7820828 | 0.67 | HTR2A (0.32) | TRPA1 | |
| SCHEMBL23032176 | 0.66 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL1772985 | 0.65 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL21399864 | 0.65 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL21312229 | 0.65 | TRPA1 (0.42) | TRPA1NOS3NOS1NOS2 | |
| SCHEMBL6671899 | 0.63 | HTR2A (0.31) | — | |
| SCHEMBL23032377 | 0.63 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL15075855 | 0.62 | — | — | |
| SCHEMBL9926021 | 0.62 | TRPA1 (0.58) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713870-B1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-07-18 | — | — | EP | claimed |
| EP-0713870-A1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-29 | — | — | EP | claimed |
| EP-0713870-B1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-6028079-A | FOR TREATING TUMOR OF MAMMAL | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0713870-A1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-29 | — | — | EP | disclosed |