Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8173497 | 0.98 | F10 (0.61) | F10LOXL2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL10922228 | 0.96 | F10 (0.59) | F10LOXL2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL2331423 | 0.92 | F10 (0.59) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL7815090 | 0.87 | F10 (0.68) | F10LOXL2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8173513 | 0.85 | F10 (0.65) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL8995527 | 0.82 | PRSS1 (0.55) | F10LOXL2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL10622182 | 0.82 | PRSS1 (0.61) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL12348108 | 0.80 | PRSS1 (0.53) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL9649899 | 0.80 | ESR1 (0.55) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL12965227 | 0.80 | PRSS1 (0.59) | F10LOXL2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |