Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.68 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PLAU | P00749 | 3/20 | 0.58 |
| ▸ | MASP2 | O00187 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.55 |
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8173513 | 0.98 | F10 (0.65) | F10LOXL2PRSS1PRSS3PRSS2 | |
| SCHEMBL7818542 | 0.87 | F10 (0.63) | F10LOXL2PRSS1PRSS3PRSS2 | |
| Hydrochloric Acid SCHEMBL8173497 | 0.85 | F10 (0.61) | F10LOXL2PRSS1PRSS3PRSS2 | |
| Hydrochloric Acid SCHEMBL10922228 | 0.84 | F10 (0.59) | F10LOXL2PRSS1PRSS3PRSS2 | |
| Hydrochloric Acid SCHEMBL2331423 | 0.84 | F10 (0.59) | F10LOXL2PRSS1PRSS3PRSS2 | |
| SCHEMBL17887809 | 0.83 | PRMT1 (0.75) | F10PRSS1PRSS3PRSS2PLAU | |
| Hydrochloric Acid SCHEMBL10925118 | 0.83 | LOXL2 (0.83) | F10LOXL2PRSS1PRSS3PRSS2 | |
| SCHEMBL20610488 | 0.82 | PRSS1 (0.68) | F10LOXL2PRSS1PRSS3PRSS2 | |
| SCHEMBL49594 | 0.81 | LOXL2 (1.00) | F10LOXL2PRSS1PRSS3PRSS2 | |
| SCHEMBL8420366 | 0.80 | PRSS1 (0.59) | F10LOXL2PRSS1PRSS3PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466961-A1 | PROLINAMIDE DERIVATIVE AS THROMBIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF | Li, Min (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |