SCHEMBL7818753

SCHEMBL7818753

CCCCOC(=O)C(N)C(C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 2/20 0.42
TSHR P16473 3/20 0.40
HPGD P15428 2/20 0.40
NOD1 Q9Y239 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PDE4D Q08499 1/20 0.38
NAAA Q02083 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 3/20 0.37
RAB9A P51151 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7373587 0.85 ALDH1A1 (0.48) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL8093944 0.85 ALDH1A1 (0.48) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL8088689 0.85 ALDH1A1 (0.48) ALDH1A1ATMHCAR2TSHRHPGD
Hydrochloric Acid SCHEMBL7377200 0.83 ALDH1A1 (0.47) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL1923182 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL7786498 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL14242995 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL1923181 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL15015941 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL3679000 0.82 ALDH1A1 (0.50) ALDH1A1ATMHCAR2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1089964-A1 HYDRAZINE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2001-04-11 EP disclosed
WO-2000000465-A1 HYDRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2000-01-06 WO disclosed