Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 10/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818956 | 1.00 | ABCC9 (0.45) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL7818959 | 1.00 | ABCC9 (0.45) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL7822051 | 1.00 | ABCC9 (0.45) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL9869960 | 0.85 | ABCC9 (0.59) | ABCC9KCNA5 | |
| SCHEMBL9869955 | 0.85 | ABCC9 (0.59) | ABCC9KCNA5 | |
| SCHEMBL9869951 | 0.85 | ABCC9 (0.59) | ABCC9KCNA5 | |
| SCHEMBL7823229 | 0.81 | ABCC9 (0.55) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL7821027 | 0.81 | ABCC9 (0.55) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL7821028 | 0.81 | ABCC9 (0.55) | ABCC9ATML3MBTL1KCNA5POLB | |
| SCHEMBL9440640 | 0.81 | ABCC9 (0.44) | ABCC9KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | claimed |
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| US-5905156-A | POTASSIUM CHANNEL ACTIVATORS AND BRONCHODILATORS | NOVARTIS AG (CH) | 1999-05-18 | — | — | US | disclosed |