SCHEMBL7819018

SCHEMBL7819018

CCCCCCCCC(Sc1nsnc1C1CN2CCC1CC2)C(C)CC

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL7811664 0.94 CHRM1 (0.40) CHRM1
SCHEMBL7812011 0.80 CHRM1 (0.47) CHRM1
SCHEMBL7810878 0.80 CHRM1 (0.65) CHRM1
SCHEMBL9559611 0.80 CHRM1 (0.65) CHRM1
Vedaclidine SCHEMBL995361 0.77 CHRM1 (0.63) CHRM1
Vedaclidine SCHEMBL995360 0.77 CHRM1 (0.63) CHRM1
SCHEMBL7811511 0.75 CHRM1 (0.62) CHRM1
SCHEMBL7818811 0.74 CHRM1 (0.60) CHRM1
SCHEMBL7818981 0.74 CHRM2 (0.51) CHRM1
SCHEMBL7818388 0.74 CHRM2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281233-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US claimed
EP-0714394-B1 ANTIPSYCHOTIC METHOD WITH THIADIAZOLE AND OXADIAZOLE DERIVATIVES NOVO NORDISK AS (DK) 2001-06-20 EP claimed
EP-0873124-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1998-10-28 EP claimed
EP-0790995-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1997-08-27 EP claimed
WO-1997025043-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1997-07-17 WO claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
EP-0873124-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1998-10-28 EP disclosed
WO-1997025043-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1997-07-17 WO disclosed