Vedaclidine

Vedaclidine

SCHEMBL995361

CCCCSc1nsnc1C1CN2CCC1CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vedaclidine SCHEMBL995360 1.00 CHRM1 (0.63) CHRM1
SCHEMBL7821561 0.96 CHRM1 (0.64) CHRM1
SCHEMBL7810878 0.95 CHRM1 (0.65) CHRM1
SCHEMBL7818351 0.95 CHRM1 (0.65) CHRM1
SCHEMBL9559611 0.95 CHRM1 (0.65) CHRM1
SCHEMBL7819046 0.94 CHRM1 (0.59) CHRM1
Vedaclidine SCHEMBL7811668 0.93 CHRM1 (0.56) CHRM1
Vedaclidine SCHEMBL9058734 0.93 CHRM1 (0.56) CHRM1
SCHEMBL9090599 0.93 CHRM1 (0.56) CHRM1
SCHEMBL7811511 0.92 CHRM1 (0.62) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
WO-2023172240-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8758816-B2 Compositions comprising azelastine and methods of use thereof MEDA PHARMACEUTICALS INC. (US) 2014-06-24 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
US-20100152147-A1 Compositions Comprising Azelastine and Methods of Use Thereof MEDA PHARMACEUTICALS INC. 2010-06-17 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
EP-0735869-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1996-10-09 EP claimed
WO-1996025154-A1 TRANSDERMAL FORMULATION ELI LILLY AND COMPANY (US) 1996-08-22 WO claimed
EP-0727208-A1 Transdermal formulation of a compound having muscarinic activity ELI LILLY AND COMPANY (US) 1996-08-21 EP claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1996013168-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO claimed
EP-0709095-A2 Method for treating anxiety using a tetrahydropyridine or azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP claimed
US-5488056-A 1,2,5-THIADIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-30 US claimed
WO-1995017180-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1995-06-29 WO claimed
EP-0544779-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-06-09 EP claimed
WO-1992003433-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1992-03-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152147-A1 Compositions Comprising Azelastine and Methods of Use Thereof TAS2R5, HRH2, IL5 CHRM1 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.