Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652672 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6703588 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29586112 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29636526 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29636499 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL608389 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9541904 | 0.76 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29636539 | 0.75 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11438183 | 0.75 | SMN1; SMN2 (0.57) | MAPTALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL3253005 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112500324-B | Method for preparing thioamide compound | 浙江大学衢州研究院 | 2022-05-13 | — | — | CN | disclosed |
| CN-112574081-B | Process for preparing arylthioamide compounds | 浙江大学衢州研究院 | 2022-05-10 | — | — | CN | disclosed |
| EP-1097137-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002859-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |