Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525886 | 0.87 | NPC1 (0.56) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4189649 | 0.85 | NPC1 (0.55) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL14359479 | 0.85 | NPC1 (0.55) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL10529630 | 0.85 | ALDH1A1 (0.57) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7963661 | 0.85 | NPC1 (0.55) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL31276466 | 0.85 | NPC1 (0.58) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL5606254 | 0.85 | NPC1 (0.52) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7128044 | 0.84 | NPC1 (0.54) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL6730228 | 0.84 | NPC1 (0.54) | NPC1ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL5783680 | 0.83 | ALDH1A1 (0.57) | NPC1ALDH1A1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077973-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS GYOGYSZERGYAR RT. (HU) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058527-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS Gyógyszergyár Rt. (HU) | 1999-11-18 | — | — | WO | disclosed |