Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047088 | 0.92 | MEN1 (0.67) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9043035 | 0.89 | KMT2A (0.62) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Difloxacin SCHEMBL29695838 | 0.88 | LMNA (1.00) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Difloxacin SCHEMBL148765 | 0.88 | LMNA (1.00) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9047179 | 0.87 | LMNA (0.61) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Difloxacin SCHEMBL203110 | 0.87 | LMNA (0.98) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Difloxacin SCHEMBL27973383 | 0.86 | LMNA (0.96) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5195883 | 0.86 | KMT2A (0.58) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL16518633 | 0.86 | MEN1 (0.85) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9668000 | 0.84 | LMNA (0.56) | MEN1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828715-B1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |