Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408620 | 1.00 | HTR2B (0.56) | HTR2BSIRT1MAPTMEN1LMNA | |
| SCHEMBL7820110 | 1.00 | HTR2B (0.56) | HTR2BSIRT1MAPTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL8932746 | 0.99 | HTR2B (0.58) | HTR2BSIRT1MAPTMEN1LMNA | |
| SCHEMBL7808861 | 0.86 | HTR2B (0.42) | HTR2BPDE4B | |
| SCHEMBL8409868 | 0.86 | HTR2B (0.42) | HTR2BPDE4B | |
| SCHEMBL7818295 | 0.83 | HTR2B (0.41) | HTR2BSIRT1MAPTMEN1KMT2A | |
| SCHEMBL8436886 | 0.81 | HTR2B (0.58) | HTR2BMAPTMEN1LMNAKMT2A | |
| SCHEMBL8831853 | 0.81 | HTR2B (0.58) | HTR2BMAPTMEN1LMNAKMT2A | |
| SCHEMBL8406878 | 0.79 | TUBB4A (0.38) | HTR2B | |
| SCHEMBL7816468 | 0.79 | TUBB4A (0.38) | HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749313-A4 | METHOD FOR TREATING 5HT 2B RECEPTOR RELATED CONDITIONS | LILLY CO ELI (US) | 2001-10-24 | — | — | EP | disclosed |
| US-5736544-A | ADMINISTERING TO TREAT MIGRAINE HEADACHES IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5688807-A | ANTIDEPRESSANTS, ANXIETY, UROGENITAL DISORDERS, HYPOTENSIVES, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| US-5663178-A | 5-HT2 RECEPTOR ANTABONISTS | ELI LILLY AND COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5643916-A | 5-HT(2B) RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5629317-A | SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0749313-A1 | METHOD FOR TREATING 5HT 2B RECEPTOR RELATED CONDITIONS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024200-A1 | METHOD FOR TREATING 5HT2B RECEPTOR RELATED CONDITIONS | ELI LILLY AND COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |