Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | KMO | O15229 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826503 | 0.89 | POLB (0.69) | POLBKMOCYP2C9CYP2C19KMT2A | |
| SCHEMBL728115 | 0.87 | KMO (0.63) | POLBKMOKMT2A | |
| SCHEMBL3678017 | 0.87 | KMO (0.63) | POLBKMOKMT2A | |
| SCHEMBL3678015 | 0.87 | KMO (0.63) | POLBKMOKMT2A | |
| SCHEMBL7822144 | 0.84 | POLB (1.00) | POLBCYP2C9CYP2C19KMT2AL3MBTL1 | |
| SCHEMBL436605 | 0.79 | KMO (0.56) | POLBKMOKMT2A | |
| SCHEMBL19642672 | 0.77 | KMO (0.75) | KMO | |
| SCHEMBL3671148 | 0.76 | KMO (0.69) | KMO | |
| SCHEMBL3671146 | 0.76 | KMO (0.69) | KMO | |
| SCHEMBL727035 | 0.76 | KMO (0.69) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |