Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435967 | 0.86 | SMN1; SMN2 (0.72) | ALDH1A1HPGDCYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL29435966 | 0.86 | SMN1; SMN2 (0.72) | ALDH1A1HPGDCYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL3527398 | 0.86 | SMN1; SMN2 (0.72) | ALDH1A1HPGDCYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL9816436 | 0.85 | SMN1; SMN2 (0.65) | ALDH1A1HPGDCYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL8011026 | 0.80 | PTPN1 (0.74) | ALDH1A1HPGDMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL8197165 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HPGDMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL8460646 | 0.79 | HPGD (0.55) | ALDH1A1HPGDMAPTCYP1A2KDM4E | |
| SCHEMBL2469662 | 0.79 | ALDH1A1 (0.70) | ALDH1A1HPGDMAPTCYP1A2KDM4E | |
| SCHEMBL4453806 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL10484311 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDMAPTCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009420-A1 | Histamine H3 Receptor Ligands | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009420-A1 | Histamine H3 Receptor Ligands | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2009126782-A1 | HISTAMINE H3 RECEPTOR LIGANDS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5780250-A | Immunoassay standards for polyaromatic hydrocarbon detection | STRATEGIC DIAGNOSTICS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1997031267-A1 | IMMUNOASSAY STANDARDS FOR POLYAROMATIC HYDROCARBON DETECTION | STRATEGIC DIAGNOSTICS, INC. (US) | 1997-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009420-A1 | Histamine H3 Receptor Ligands | HRH3, HRH4, HRH2 | ALDH1A1 1218/4885HPGD 806/4885MAPT 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.