SCHEMBL7821079

SCHEMBL7821079

CCN(c1ccccc1)c1ccc(C=NN(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.50
GAA P10253 4/20 0.50
MAPK1 P28482 3/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 6/20 0.48
MEN1 O00255 5/20 0.48
ALDH1A1 P00352 9/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MCL1 Q07820 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
G6PC1 P35575 2/20 0.45
NR3C2 P08235 1/20 0.43
USP2 O75604 1/20 0.42
POLB P06746 2/20 0.41
EIF4H Q15056 1/20 0.41
KDM4E B2RXH2 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7821078 1.00 MAPT (0.50) MAPTGAAMAPK1HTTKMT2A
SCHEMBL122069 0.87 MAPT (0.61) MAPTGAAMAPK1HTTKMT2A
SCHEMBL122070 0.87 MAPT (0.61) MAPTGAAMAPK1HTTKMT2A
SCHEMBL16425719 0.85 MAPT (0.49) MAPTGAAMAPK1HTTKMT2A
SCHEMBL332093 0.84 CYP1A2 (0.53) MAPTGAAMAPK1HTTKMT2A
SCHEMBL332094 0.84 CYP1A2 (0.53) MAPTGAAMAPK1HTTKMT2A
SCHEMBL9453718 0.83 GAA (0.41) MAPTGAAMAPK1HTTKMT2A
SCHEMBL12572177 0.81 MEN1 (0.49) MAPTGAAMAPK1HTTKMT2A
SCHEMBL331931 0.81 ALDH1A1 (0.62) MAPTMAPK1KMT2AMEN1ALDH1A1
SCHEMBL12637395 0.81 SMN1; SMN2 (0.53) MAPTGAAMAPK1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780363-B1 Bisazo-benzofuran compounds, their use as charge carrier generating compounds SHARP KK (JP) 2001-09-26 EP disclosed
US-6022655-A CHARGE TRANSFER COMPOUND SHARP KABUSHIKI KAISHA (JP) 2000-02-08 US disclosed
US-5853930-A Electrophotographic photoconductors using bisazo compounds SHARP KABUSHIKI KAISHA (JP) 1998-12-29 US disclosed
EP-0780363-A1 Bisazo-benzofuran compounds, their use as charge carrier generating compounds and intermediates for their preparation SHARP KABUSHIKI KAISHA (JP) 1997-06-25 EP disclosed
US-5501930-A Electrophotographic photoreceptor containing enamine derivative SHARP KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
US-5389479-A Excellent sensitivity in positive charge; multilayer consists of charge generating and charge transferring layer SHARP KABUSHIKI KAISHA (JP) 1995-02-14 US disclosed