Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809459 | 0.90 | FFAR1 (0.47) | ACACBNPC1RAB9AFFAR1PTPN7 | |
| SCHEMBL11807154 | 0.78 | CYP1B1 (0.60) | ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11815915 | 0.77 | AKR1C3 (0.51) | ACACBNPC1ALDH1A1FFAR1 | |
| SCHEMBL852441 | 0.77 | GAA (0.46) | ACACBSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL25218518 | 0.76 | PTPN7 (0.45) | ACACBFFAR1PTPN7ASIC3CYP1A2 | |
| Anthracene SCHEMBL2354665 | 0.75 | FFAR3 (0.50) | SMN1; SMN2NPC1ALDH1A1RAB9APTPN7 | |
| Anthracene SCHEMBL4231335 | 0.75 | FFAR3 (0.50) | SMN1; SMN2NPC1ALDH1A1RAB9APTPN7 | |
| Naphthalene SCHEMBL6034647 | 0.75 | FFAR3 (0.56) | SMN1; SMN2NPC1ALDH1A1RAB9APTPN7 | |
| Naphthalene SCHEMBL7096694 | 0.75 | FFAR3 (0.56) | SMN1; SMN2NPC1ALDH1A1RAB9APTPN7 | |
| SCHEMBL11814749 | 0.74 | KDM4E (0.53) | SMN1; SMN2NPC1ALDH1A1RAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |