Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Nitro-2-Phenylpropylaminobenzoic Acid [Nppb] SCHEMBL7821604 | 0.87 | MAPT (0.82) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| 5-Nitro-2-Phenylpropylaminobenzoic Acid [Nppb] SCHEMBL29375101 | 0.81 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| 5-Nitro-2-Phenylpropylaminobenzoic Acid [Nppb] SCHEMBL159244 | 0.81 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4217741 | 0.78 | MAPT (0.93) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6374917 | 0.74 | MAPT (0.82) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL3029764 | 0.74 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL14280729 | 0.70 | CDK2 (0.77) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL21437337 | 0.69 | KMT2A (0.65) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL28469904 | 0.68 | CES2 (0.52) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27577353 | 0.68 | MAPT (0.69) | MAPTALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |