Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL7821767 | 0.81 | KDM4E (0.68) | KDM4EMAPTKMT2AMEN1EGFR | |
| SCHEMBL7821773 | 0.80 | KDM4E (0.53) | KDM4EMAPTKMT2AMEN1EGFR | |
| SCHEMBL21457685 | 0.77 | KDM4E (0.65) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL21457688 | 0.77 | KDM4E (0.65) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285559 | 0.73 | KDM4E (1.00) | KDM4EMAPTKMT2AMEN1EGFR | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL2057244 | 0.73 | KDM4E (1.00) | KDM4EMAPTKMT2AMEN1EGFR | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL29881895 | 0.73 | KDM4E (1.00) | KDM4EMAPTKMT2AMEN1EGFR | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285555 | 0.73 | KDM4E (1.00) | KDM4EMAPTKMT2AMEN1EGFR | |
| SCHEMBL21457224 | 0.73 | KDM4E (0.70) | KDM4EMAPTKMT2AMEN1EGFR | |
| SCHEMBL21457227 | 0.73 | KDM4E (0.70) | KDM4EMAPTKMT2AMEN1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |