Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821773 | 0.83 | KDM4E (0.53) | KDM4EMEN1KMT2AEGFRALDH1A1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285555 | 0.83 | KDM4E (1.00) | KDM4EMEN1KMT2AEGFRCISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL2057244 | 0.83 | KDM4E (1.00) | KDM4EMEN1KMT2AEGFRCISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL29881895 | 0.83 | KDM4E (1.00) | KDM4EMEN1KMT2AEGFRCISD1 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL1285559 | 0.83 | KDM4E (1.00) | KDM4EMEN1KMT2AEGFRCISD1 | |
| SCHEMBL7821768 | 0.81 | KDM4E (0.56) | KDM4EMEN1KMT2AEGFRALDH1A1 | |
| Alpha-Cyano-4-Hydroxycinnamic Acid SCHEMBL8045415 | 0.78 | KDM4E (0.88) | KDM4EMEN1KMT2AEGFRCISD1 | |
| SCHEMBL20615263 | 0.76 | KDM4E (0.69) | KDM4EKMT2AEGFRCISD1SLC16A3 | |
| SCHEMBL28791205 | 0.76 | KDM4E (0.69) | KDM4EKMT2AEGFRCISD1SLC16A3 | |
| SCHEMBL7821777 | 0.75 | LMNA (0.39) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |