Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539315 | 1.00 | KMT2A (0.59) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL31670446 | 0.84 | AKR1C3 (0.53) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL6393137 | 0.84 | TSHR (0.49) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL17227611 | 0.83 | KMT2A (0.62) | KMT2AMEN1TSHRPOLBMAPT | |
| SCHEMBL3282591 | 0.82 | AKR1C3 (0.53) | TSHRHPGDRORCAKR1C3 | |
| SCHEMBL6398959 | 0.80 | AKR1C3 (0.56) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL23657779 | 0.79 | KMT2A (0.50) | KMT2AMEN1ALDH1A1TSHRHPGD | |
| SCHEMBL5069905 | 0.79 | TSHR (0.49) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL7076783 | 0.79 | AKR1C3 (0.52) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL735675 | 0.79 | TSHR (0.81) | KMT2AALDH1A1TSHRPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |