SCHEMBL78219

SCHEMBL78219

CCCC=Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.53
HTR2A P28223 3/20 0.50
IDO1 P14902 2/20 0.48
PAM P19021 1/20 0.48
MAOB P27338 1/20 0.46
RELA Q04206 1/20 0.45
HDAC3 O15379 1/20 0.43
TNKS O95271 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108128 1.00 SIGMAR1 (0.53) SIGMAR1HTR2AIDO1PAMMAOB
Benzene SCHEMBL1226215 1.00 SIGMAR1 (0.53) SIGMAR1HTR2AIDO1PAMMAOB
SCHEMBL28490848 1.00 SIGMAR1 (0.53) SIGMAR1HTR2AIDO1PAMMAOB
Benzene SCHEMBL1226219 1.00 SIGMAR1 (0.53) SIGMAR1HTR2AIDO1PAMMAOB
Anthracene SCHEMBL28105538 0.90 TLR8 (0.47) SIGMAR1HTR2AIDO1PAMRELA
SCHEMBL28386776 0.87 CA1 (0.46) SIGMAR1HTR2ARELAHDAC3HDAC4
SCHEMBL27816694 0.87 HTR2A (0.49) SIGMAR1HTR2AIDO1PAMRELA
SCHEMBL15573543 0.86 SIGMAR1 (0.50) SIGMAR1HTR2AIDO1PAMMAOB
SCHEMBL1295478 0.86 SIGMAR1 (0.50) SIGMAR1HTR2AIDO1PAMMAOB
SCHEMBL22082 0.86 SIGMAR1 (0.50) SIGMAR1HTR2AIDO1PAMMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4977 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121575410-A Phosphorus-free high-temperature corrosion inhibitor and preparation method thereof 金浦新材料股份有限公司 2026-02-27 CN claimed
US-20260016614-A1 Optical Compensation Films Based on Stretched Cyclic Block Copolymers AKRON POLYMER SYSTEMS INC (US) 2026-01-15 US claimed
US-12503585-B2 Silane functionalized styrenic block copolymer Kraton Corporation (US) 2025-12-23 US claimed
EP-4644481-A1 POLYMER COMPOSITIONS AND METHODS OF PREPARATION THEREOF Kraton Polymers Nederland B.V. (NL) 2025-11-05 EP claimed
US-20250333572-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS TRINSEO EUROPE GMBH (CH) 2025-10-30 US claimed
US-12331243-B2 Cement compositions and methods of preparation thereof Kraton Corporation (US) 2025-06-17 US claimed
US-20250188274-A1 LOW VOLATILE ORGANIC COMPOUND (VOC) THERMOPLASTIC COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-06-12 US claimed
EP-4555008-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS Trinseo Europe GmbH (CH) 2025-05-21 EP claimed
US-12275822-B2 Foam, composite material, and foaming composition INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2025-04-15 US claimed
WO-2025075394-A1 RESIN COMPOSITION COMPRISING HALOGEN-FREE COMPOSITE FLAME RETARDANT AND MOLDED ARTICLE MANUFACTURED BY MOLDING SAME 금호석유화학 주식회사 2025-04-10 WO claimed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US claimed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US claimed
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP claimed
EP-0047109-B1 RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP claimed
EP-0030716-B1 CHLORINATED PVC BLENDS WITH IMPROVED PROCESSABILITY The B.F. GOODRICH Company (US) 1984-02-08 EP claimed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP claimed
US-4304884-A A-ALKYLSTYRENE-VINYLBENZENE OR ACRYLATE-NITRILE TERPOLYMER THE B. F. GOODRICH COMPANY (US) 1981-12-08 US claimed
EP-0030716-A1 Chlorinated PVC blends with improved processability The B.F. GOODRICH Company (US) 1981-06-24 EP claimed
US-4208506-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1980-06-17 US claimed
US-4068676-A RELEASE AGENTS HALLIBURTON COMPANY (US) 1978-01-17 US claimed