Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 16/20 | 0.62 |
| ▸ | DBF4 | Q9UBU7 | 16/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834057 | 0.81 | CDC7 (0.59) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL7822179 | 0.81 | CDC7 (0.38) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL7834634 | 0.79 | AKT2 (0.40) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL7830582 | 0.78 | CDC7 (0.56) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL29805133 | 0.77 | CDC7 (0.60) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL7832920 | 0.77 | CDC7 (0.61) | CDC7DBF4HPGDLMNAHSD17B10 | |
| SCHEMBL2120065 | 0.76 | CDC7 (1.00) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL29851680 | 0.76 | CDC7 (1.00) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL7832937 | 0.76 | ALDH1A1 (0.40) | CDC7DBF4HPGDALDH1A1LMNA | |
| SCHEMBL10435363 | 0.75 | CYP1A2 (1.00) | CDC7DBF4HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802914-B1 | ARYL- AND HETEROARYL- PURINE AND PYRIDOPYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-06-06 | — | — | EP | claimed |
| EP-0802914-A1 | ARYL AND HETEROARYL PURINE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-10-29 | — | — | EP | claimed |
| WO-1997018212-A1 | ARYL AND HETEROARYL PURINE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-05-22 | — | — | WO | claimed |
| EP-0802914-B1 | ARYL- AND HETEROARYL- PURINE AND PYRIDOPYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-06-06 | — | — | EP | disclosed |
| US-5965563-A | NOVEL PURINE DERIVATIVES SUCH AS N6-(2-OXINDOL-5-YL) ADENINE, METHODS OF SYNTHESIZING THEM; USE AS TYROSINE KINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-10-12 | — | — | US | disclosed |