Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822334 | 1.00 | ALDH1A1 (0.67) | ALDH1A1GLAHTTSMN1; SMN2CYP2C9 | |
| SCHEMBL4320215 | 0.84 | HTT (0.68) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL4320209 | 0.84 | HTT (0.68) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL17368531 | 0.83 | HTT (0.60) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL17434438 | 0.82 | ALDH1A1 (0.68) | ALDH1A1GLASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL17434434 | 0.82 | ALDH1A1 (0.68) | ALDH1A1GLASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL11332313 | 0.81 | KMT2A (0.71) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL10874419 | 0.80 | HTT (0.56) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL10874425 | 0.80 | HTT (0.56) | ALDH1A1HTTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL14675747 | 0.79 | MAPT (0.74) | ALDH1A1SMN1; SMN2CYP2C19LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |