Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 9/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783318 | 0.88 | NR1H2 (0.36) | TSPOPDK2PTGES2PTGESTBXAS1 | |
| SCHEMBL782648 | 0.86 | PDK2 (0.32) | TSPOPDK2 | |
| SCHEMBL803029 | 0.86 | PDK2 (0.32) | TSPOPDK2 | |
| SCHEMBL14960715 | 0.85 | PDK2 (0.33) | TSPOPDK2 | |
| SCHEMBL14960705 | 0.85 | PGR (0.30) | PDK2 | |
| SCHEMBL14960716 | 0.84 | PDK2 (0.33) | TSPOPDK2 | |
| SCHEMBL801982 | 0.84 | PDK2 (0.31) | PDK2 | |
| SCHEMBL15696444 | 0.83 | PDK2 (0.34) | TSPOPDK2 | |
| SCHEMBL21527134 | 0.83 | PDK2 (0.34) | TSPOPDK2 | |
| SCHEMBL21527223 | 0.83 | PDK2 (0.34) | TSPOPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9537105-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-9126970-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | TSPO 191/4885PDK2 2085/4885NR4A2 1795/4885 |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | TSPO 191/4885PDK2 2085/4885NR4A2 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.