Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819559 | 0.84 | HTR7 (0.41) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7816875 | 0.84 | HTR7 (0.38) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7808397 | 0.84 | HTR7 (0.39) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7820294 | 0.81 | HTR7 (0.45) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7818350 | 0.79 | MAPT (0.41) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7977455 | 0.78 | HTR7 (0.40) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7822680 | 0.78 | ABCB1 (0.41) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7819153 | 0.76 | GRIN1 (0.41) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7994758 | 0.76 | HTR7 (0.41) | HTR7DRD2DRD3DRD4MEN1 | |
| SCHEMBL7818373 | 0.76 | HTR7 (0.44) | HTR7DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749971-B1 | Thiopyran derivatives | SUNTORY LTD (JP) | 2001-03-14 | — | — | EP | disclosed |