Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7458674 | 0.99 | CHRM5 (0.43) | CHRM5CHRM3CHRM1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7470108 | 0.95 | DRD2 (0.41) | CHRM5CHRM3CHRM1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL7831195 | 0.95 | CHRM5 (0.40) | CHRM5CHRM3CHRM1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7463780 | 0.94 | CHRM5 (0.40) | CHRM5CHRM3CHRM1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL8884595 | 0.94 | CHRM5 (0.41) | CHRM5CHRM3CHRM1POLBMEN1 | |
| SCHEMBL7816134 | 0.94 | CCR3 (0.39) | CHRM5CHRM3CHRM1DRD2DRD3 | |
| SCHEMBL7826747 | 0.94 | DRD3 (0.39) | CHRM5CHRM3CHRM1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7464849 | 0.94 | CHRM5 (0.40) | CHRM5CHRM3CHRM1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7463300 | 0.93 | DRD3 (0.39) | CHRM5CHRM3CHRM1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7464558 | 0.93 | CCR3 (0.39) | CHRM5CHRM3CHRM1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | claimed |
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |