Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FER | P16591 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31654001 | 1.00 | IDO1 (0.54) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL7822762 | 1.00 | IDO1 (0.54) | IDO1TDO2LRRK2MAOAMAOB | |
| Glycolic Acid SCHEMBL6888173 | 0.75 | LRRK2 (0.64) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL17169398 | 0.74 | IDO1 (0.51) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL7006381 | 0.74 | TDP1 (0.69) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL5619605 | 0.73 | IDO1 (0.50) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL5619602 | 0.73 | IDO1 (0.50) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL14515139 | 0.73 | IDO1 (0.50) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL30681308 | 0.73 | IDO1 (0.57) | IDO1TDO2LRRK2MAOAMAOB | |
| SCHEMBL7304930 | 0.73 | IDO1 (0.57) | IDO1TDO2LRRK2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |