SCHEMBL7822987

SCHEMBL7822987

Cc1c(N(C)C(=O)[C@@H]2CCCN2)ccc2nc(N[C@@H](C)c3ccccc3)oc(=O)c12

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ELANE P08246 15/20 0.64
CTRB1 P17538 8/20 0.64
SCN4A P35499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6505357 0.78 ELANE (0.66) ELANECTRB1
SCHEMBL6505035 0.78 ELANE (0.71) ELANECTRB1
SCHEMBL6500524 0.75 ELANE (0.73) ELANECTRB1
SCHEMBL6496728 0.74 ELANE (0.70) ELANECTRB1
SCHEMBL6497124 0.71 ELANE (0.72) ELANECTRB1
SCHEMBL6496686 0.71 ELANE (0.72) ELANECTRB1
SCHEMBL6497278 0.71 ELANE (0.72) ELANECTRB1
SCHEMBL6496017 0.71 CTRB1 (0.77) ELANECTRB1
SCHEMBL6498365 0.70 CTRB1 (1.00) ELANECTRB1
SCHEMBL6503648 0.70 ELANE (0.61) ELANECTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122245-A2 2-Amino-benzoxazinones for the treatment of viral infections G.D. Searle & Co. (US) 2001-08-08 EP disclosed