SCHEMBL7823017

SCHEMBL7823017

CCCN1C(=O)[C@@H](N(C(N)=O)c2cccc(C)c2)N=C(N(C)C2CCCCC2)c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 12/20 0.45
BDKRB1 P46663 1/20 0.38
CCKAR P32238 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9276253 1.00 CCKBR (0.45) CCKBRBDKRB1CCKAR
SCHEMBL9428816 0.84 CCKBR (0.63) CCKBRBDKRB1CCKAR
SCHEMBL7822689 0.77 CCKBR (0.69) CCKBRCCKAR
SCHEMBL7816105 0.77 CCKBR (0.69) CCKBRCCKAR
SCHEMBL9008683 0.77 CCKBR (0.45) CCKBRBDKRB1CCKAR
SCHEMBL9008792 0.77 CCKBR (0.45) CCKBRBDKRB1CCKAR
SCHEMBL9279525 0.76 CCKBR (0.66) CCKBRBDKRB1
SCHEMBL9260751 0.73 BDKRB1 (0.49) CCKBRBDKRB1CCKAR
SCHEMBL9368599 0.73 CCKBR (0.57) CCKBR
SCHEMBL9008684 0.73 BDKRB1 (0.45) CCKBRBDKRB1CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652871-B1 BENZODIAZEPINE DERIVATIVES MERCK SHARP & DOHME (GB) 2001-10-17 EP disclosed