Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937519 | 0.95 | NPC1 (0.54) | MGLLNPC1RAB9AMAPTTP53 | |
| SCHEMBL6942718 | 0.87 | MGLL (0.56) | MGLLNPC1RAB9AMAPTNAAA | |
| SCHEMBL7646600 | 0.84 | MGLL (0.53) | MGLLNPC1RAB9AMAPTNAAA | |
| SCHEMBL27358389 | 0.82 | MGLL (0.54) | MGLLNPC1MAPTNAAAKMT2A | |
| SCHEMBL26757997 | 0.82 | MGLL (0.54) | MGLLNPC1RAB9AMAPTHTT | |
| SCHEMBL7371656 | 0.81 | KMT2A (0.70) | NPC1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL11318826 | 0.81 | KMT2A (0.70) | NPC1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL8384101 | 0.81 | MGLL (0.53) | MGLLNPC1RAB9AMAPTHTT | |
| SCHEMBL28860063 | 0.81 | SMN1; SMN2 (0.60) | MGLLNPC1RAB9AMAPTHTT | |
| SCHEMBL27452022 | 0.81 | SMN1; SMN2 (0.57) | MGLLNPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |