Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 14/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7837985 | 0.89 | KMT2A (0.51) | KMT2AALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL7823387 | 0.87 | KMT2A (0.48) | KMT2ATOP1TOP2ATOP2B | |
| SCHEMBL13282783 | 0.85 | KMT2A (0.49) | KMT2ATOP1TOP2ATOP2B | |
| SCHEMBL19881448 | 0.85 | KMT2A (0.49) | KMT2ATOP1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL7835276 | 0.84 | KMT2A (0.48) | KMT2ATOP1TOP2ATOP2B | |
| SCHEMBL8666279 | 0.83 | KMT2A (0.49) | KMT2AALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL8667420 | 0.83 | KMT2A (0.50) | KMT2ATOP1TOP2ATOP2B | |
| SCHEMBL7823113 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL2617022 | 0.78 | CHRM2 (0.53) | KMT2AALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL27368444 | 0.78 | MEN1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| CN-1053668-C | Novel compound, process for producing the same, and antitumor agent | DAINIPPON PHARMACEUTICAL CO (JP) | 2000-06-21 | — | — | CN | disclosed |
| US-5817669-A | A COMPOUND CONTAINING 1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1158614-A | Novel compound, process for producing the same, and antitumor agent | DAINIPPON PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |
| EP-0787726-A1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |