Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747566 | 0.85 | KDM4E (0.47) | CHRM2ALDH1A1DPP4KMT2AKCNH2 | |
| SCHEMBL18739877 | 0.84 | KMT2A (0.42) | CHRM2ALDH1A1POLBCHRM1OPRM1 | |
| SCHEMBL10501993 | 0.83 | KDM4E (0.54) | CHRM2ALDH1A1POLBOPRM1DPP4 | |
| SCHEMBL10743308 | 0.83 | CSF1R (0.47) | CHRM2ALDH1A1DPP4KMT2AKCNH2 | |
| SCHEMBL10554614 | 0.81 | KCNH2 (0.48) | CHRM2ALDH1A1DPP4KMT2AKCNH2 | |
| SCHEMBL10747557 | 0.81 | DPP4 (0.45) | CHRM2ALDH1A1DPP4KMT2AKCNH2 | |
| SCHEMBL9838735 | 0.81 | KMT2A (0.69) | CHRM2ALDH1A1POLBCHRM1OPRM1 | |
| SCHEMBL13576371 | 0.81 | KMT2A (0.69) | CHRM2ALDH1A1POLBCHRM1OPRM1 | |
| SCHEMBL4575476 | 0.81 | KMT2A (0.69) | CHRM2ALDH1A1POLBCHRM1OPRM1 | |
| SCHEMBL7823113 | 0.80 | KMT2A (0.52) | CHRM2ALDH1A1POLBCHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2012-04-19 | — | — | US | disclosed |
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | RNASE1, DCLRE1B, FEN1 | CHRM2 4883/4885ALDH1A1 1675/4885POLB 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.