Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838480 | 0.96 | HPGD (0.43) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8446918 | 0.90 | HPGD (0.46) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8853553 | 0.89 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8853559 | 0.89 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8853902 | 0.88 | RARB (0.43) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10000256 | 0.88 | RARB (0.43) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8853910 | 0.88 | RARB (0.43) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8450107 | 0.85 | NPC1 (0.52) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8773149 | 0.85 | NPC1 (0.52) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8447353 | 0.85 | NPC1 (0.52) | RARBNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5279299-A | — | — | None | — | — | JP | disclosed |
| EP-0552658-B1 | 3-Cyclohexyl propionic acid derivatives and their use in ferroelectric liquid crystal mixtures | AVENTIS RES & TECH GMBH & CO (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-5679792-A | ELECTROOPTICS, DISPLAYS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| JP-H05279299-A | 3-CYCLOHEXYLPROPIONIC ACID AND USED THEREOF IN FERROELECTRIC LIQUID CRYSTAL MIXTURE | HOECHST AG | 1993-10-26 | — | — | JP | disclosed |
| EP-0552658-A1 | 3-Cyclohexyl propionic acid derivatives and their use in ferroelectric liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |