Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853559 | 1.00 | RARB (0.44) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL10000256 | 0.95 | RARB (0.43) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8853910 | 0.95 | RARB (0.43) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8853902 | 0.95 | RARB (0.43) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL7838480 | 0.93 | HPGD (0.43) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9157429 | 0.92 | SMN1; SMN2 (0.44) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9563672 | 0.90 | RAB9A (0.38) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL7823480 | 0.89 | RARB (0.46) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8853505 | 0.89 | RARB (0.54) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8853512 | 0.89 | RARB (0.54) | RARBNPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679792-A | ELECTROOPTICS, DISPLAYS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0552658-A1 | 3-Cyclohexyl propionic acid derivatives and their use in ferroelectric liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |