SCHEMBL7823734

SCHEMBL7823734

NC(C(=O)O)C(=O)O.O=C(O)C(Cc1ccccc1)=NO

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 13/20 0.77
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7823733 1.00 CTBP2 (0.77) CTBP2CYP1A2CYP2C19CA1CA2
SCHEMBL29346017 0.88 CTBP2 (1.00) CTBP2CYP1A2CYP2C19CA1CA2
SCHEMBL28552907 0.88 CTBP2 (1.00) CTBP2CYP1A2CYP2C19CA1CA2
SCHEMBL31264411 0.77 CTBP2 (0.71) CTBP2CYP2C19CA1CA2CA12
SCHEMBL3084459 0.75 CTBP2 (0.75) CTBP2CA1CA2CA12CA9
SCHEMBL3084457 0.75 CTBP2 (0.75) CTBP2CA1CA2CA12CA9
SCHEMBL3084456 0.75 CTBP2 (0.75) CTBP2CA1CA2CA12CA9
SCHEMBL5288297 0.74 ALPI (0.53) CYP1A2CYP2C19SLC1A3SLC1A2SLC1A1
SCHEMBL11282868 0.73 CTBP2 (1.00) CTBP2CYP1A2CYP2C19CA1CA2
SCHEMBL7877787 0.73 CTBP2 (0.71) CTBP2CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed