SCHEMBL7877787

SCHEMBL7877787

CC(=O)C(Cc1ccccc1)=NO

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 13/20 0.71
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
AKR1B1 P15121 1/20 0.50
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7877784 1.00 CTBP2 (0.71) CTBP2CA1CA2CES2CES1
SCHEMBL28552907 0.83 CTBP2 (1.00) CTBP2CA1CA2CES2CES1
SCHEMBL29346017 0.83 CTBP2 (1.00) CTBP2CA1CA2CES2CES1
SCHEMBL3084456 0.83 CTBP2 (0.75) CTBP2CA1CA2CES2CES1
SCHEMBL3084457 0.83 CTBP2 (0.75) CTBP2CA1CA2CES2CES1
SCHEMBL3084459 0.83 CTBP2 (0.75) CTBP2CA1CA2CES2CES1
SCHEMBL19626039 0.82 CTBP2 (0.73) CTBP2
SCHEMBL3391716 0.82 CTBP2 (0.62) CTBP2CA1CA2CES2CES1
SCHEMBL10194479 0.81 CTBP2 (0.67) CTBP2CA1CA2CES2CES1
SCHEMBL7866062 0.81 CTBP2 (0.52) CTBP2CES2CES1AKR1B1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1206914-C Pesticide containing 0-benzyl oximeether derivative and its use NOVARTIS AG (CH) 2005-06-22 CN disclosed
CN-1075490-C O-benzyl oxime ether derivatives and their use in crop protection compositions BAYER AG (DE) 2001-11-28 CN disclosed
US-6319925-B1 MICROBICIDAL, ACARICIDAL AND INSECTICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
CN-1309898-A Pesticide containing 0-benzyl oximeether derivative and its use NOVARTIS AG (CH) 2001-08-29 CN disclosed
EP-0848701-B1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 2000-05-17 EP disclosed
CN-1189150-A O-benzyl oxime ether derivatives and their use in crop protection compositions NOVATIS LTD (CH) 1998-07-29 CN disclosed
EP-0848701-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS Novartis AG (CH) 1998-06-24 EP disclosed
WO-1997001530-A1 O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE IN CROP PROTECTION COMPOSITIONS NOVARTIS AG (CH) 1997-01-16 WO disclosed
US-4442291-A INTERMEDIATE FOR ANTIPSYCHOTIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1984-04-10 US disclosed
US-4349678-A NEUROLEPTIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1982-09-14 US disclosed
US-4260762-A NEUROLEPTICS HOFFMANN-LA ROCHE INC. (US) 1981-04-07 US disclosed
US-4229579-A OPTICAL BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed
US-4144243-A OPTICAL BRIGHTENERS FOR TEXTILES AND LACQUEARS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4005098-A BRIGHTENING AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US disclosed