Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827623 | 1.00 | ABCC9 (0.49) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7827620 | 1.00 | ABCC9 (0.49) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7822793 | 0.91 | ABCC9 (0.51) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7822798 | 0.91 | ABCC9 (0.51) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7822791 | 0.91 | ABCC9 (0.51) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7821028 | 0.89 | ABCC9 (0.55) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7821027 | 0.89 | ABCC9 (0.55) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7823229 | 0.89 | ABCC9 (0.55) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7825496 | 0.87 | ABCC9 (0.49) | ABCC9LMNAABCC8KCNJ11KCNJ8 | |
| SCHEMBL7825500 | 0.87 | ABCC9 (0.49) | ABCC9LMNAABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | claimed |
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| US-5905156-A | POTASSIUM CHANNEL ACTIVATORS AND BRONCHODILATORS | NOVARTIS AG (CH) | 1999-05-18 | — | — | US | disclosed |