Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | TXN | P10599 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6157868 | 0.99 | KMT2A (0.36) | KMT2AMEN1BLMAPPTXN | |
| SCHEMBL7836074 | 0.94 | MEN1 (0.35) | KMT2AMEN1BLMAPPTXN | |
| Hydrochloric Acid SCHEMBL6159137 | 0.93 | MEN1 (0.34) | KMT2AMEN1BLMAPPTXN | |
| SCHEMBL6158502 | 0.92 | KMT2A (0.37) | KMT2AMEN1BLMAPPTXN | |
| SCHEMBL6158156 | 0.92 | KMT2A (0.40) | KMT2AMEN1BLMAPPBRD4 | |
| Hydrochloric Acid SCHEMBL6160343 | 0.91 | KMT2A (0.36) | KMT2AMEN1BLMAPPTXN | |
| Hydrochloric Acid SCHEMBL6157511 | 0.91 | KMT2A (0.39) | KMT2AMEN1BLMAPPADRA2A | |
| SCHEMBL6956974 | 0.90 | ESR1 (0.41) | KMT2AMEN1BLMAPPADRA2A | |
| SCHEMBL7833131 | 0.90 | CDK9 (0.35) | KMT2AMEN1BRD4ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6967452 | 0.90 | ESR1 (0.41) | KMT2AMEN1BLMAPPADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |