Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079520 | 0.84 | SMN1; SMN2 (0.83) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL761148 | 0.79 | CHRM1 (0.71) | SMN1; SMN2NPC1RAB9ACHRM1MAPT | |
| SCHEMBL3065316 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| Procodazole SCHEMBL349966 | 0.76 | CHRM1 (1.00) | NPC1RAB9ACHRM1MAPTALDH1A1 | |
| Procodazole SCHEMBL29404024 | 0.76 | CHRM1 (1.00) | NPC1RAB9ACHRM1MAPTALDH1A1 | |
| Procodazole SCHEMBL838841 | 0.76 | CHRM1 (1.00) | NPC1RAB9ACHRM1MAPTALDH1A1 | |
| SCHEMBL9866161 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| Water SCHEMBL10769741 | 0.76 | CHRM1 (0.55) | SMN1; SMN2NPC1RAB9ACHRM1MAPT | |
| SCHEMBL3506863 | 0.76 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1LMNAKMT2A | |
| Bromide SCHEMBL11317742 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0218753-A1 | Image-recieving element for the silver salt diffusion transfer reversal process | AGFA-GEVAERT N.V. (BE) | 1987-04-22 | — | — | EP | disclosed |