Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 4/20 | 0.55 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825008 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14429836 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7821977 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7828359 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7821548 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7825380 | 1.00 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7827663 | 0.99 | CYP2C9 (0.69) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7820705 | 0.94 | CYP2C9 (0.71) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7636178 | 0.92 | SOAT1 (0.68) | CYP2C9HPGDKMT2AALDH1A1SOAT1 | |
| SCHEMBL5840193 | 0.92 | SOAT1 (0.68) | CYP2C9HPGDKMT2AALDH1A1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |